1761 0 T-Coffee (SOAP) SOAP

SAWSDL: http://mango.ctegd.uga.edu/jkissingLab/SWS/Wsannotation/resources/tcoffee.sawsdl

http://www.ebi.ac.uk/Tools/webservices/services/msa/tcoffee_soap

T-Coffee is a multiple sequence alignment program. Multiple sequence alignment programs are meant to align a set of sequences previously gathered using other programs such as BLAST or FASTA. The main characteristic of T-Coffee is that it will allow you to combine results obtained with several alignment methods. For instance if you have an alignment coming from ClustalW, an other alignment coming from Dialign, and a structural alignment of some of your sequences, T-Coffee will combine all that information and produce a new multiple sequence having the best agreement with all these methods. By default, T-Coffee will compare all your sequences two by two, producing a global alignment and a series of local alignments (using lalign). The program will then combine all these alignments into a multiple alignment.

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Goujon M., McWilliam H., Li W., Valentin F., Squizzato S., Paern J. and Lopez R. (2010)
"A new bioinformatics analysis tools framework at EMBL-EBI."
Nucleic Acids Res. 38:W695-9
PMID: 20439314 (http://www.ebi.ac.uk/citexplore/citationDetails.do?externalId=20439314&dataSource=MED)
DOI: 10.1093/nar/gkq313 (http://dx.doi.org/10.1093/nar/gkq313)

Notredame C., Higgins D.G. and Heringa J. (2000)
"T-Coffee: A novel method for fast and accurate multiple sequence alignment."
J. Mol. Biol. 302(1):205-17.
PMID: 10964570 (http://www.ebi.ac.uk/citexplore/citationDetails.do?externalId=10964570&dataSource=MED)
DOI: 10.1006/jmbi.2000.4042 (http://dx.doi.org/10.1006/jmbi.2000.4042)