Provider:
National Research Council Italy (CNR)
Location:
not available
Submitter / Source:
itb-bari (6 months ago)
Base URL:
http://spank.ba.itb.cnr.it/cgi-bin/engineDB_12_09.pl
WSDL Location:
http://spank.ba.itb.cnr.it/docs/engineDB_12_09.wsdl(download last cached WSDL file)
Documentation URL(s): itb-bari (6 months ago)http://funcnet.eu/partners-and-predictors/enginedb/
Login to add a documentation URL Description(s): itb-bari (6 months ago)GENe AnaloGue FINdEr (ENGINE) uses semantic similarity between GO terms to score proteins for similarity of function. Even if two proteins have no actual GO annotations directly in common, they may be annotated with terms that are very closely related, by virtue of their proximity in the GO graph and mutual information content. ENGINE was designed to detect such implicit associations via large-scale grid-based statistical analysis, and the repository ‘engineDB’ (http://spank.ba.itb.cnr.it/engine) contains the results of this analysis.
The service runs on data generated with the Gene Ontology version Dec. 2009
The engineDB service accepts two lists of UniProt Accession Numbers, a query set (unknown or poorly-understood functions) and a reference set (distinct and well-characterized function) predicting whether the query proteins are involved in the same processes or phenomena as proteins from the reference set.
The output is a list of quadruplets: query protein, reference protein, raw score, p-value.
Login to add a description License(s): None Login to add license info Cost: No info yet Login to add cost info Usage Conditions: No info yet Login to add usage conditions info Contact Info: None Login to add contact info Publications: for this service. This can be a URI to the publication and/or a DOI. None Login to add publication info Citations: None Login to add a citation