Web Service Off-target effects REST Us

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Overview

Provider:
www-creative-biogene-com

Location:
United States Us

Submitter/Source:
Bennie GeorgeUs (15 days ago)

Base URL:
https://www.creative-biogene.com/crispr-cas9/crispr-off-target-effects-analysis.html

Description(s):
by Bennie George (15 days ago)

Cas9, which is a nuclease, can be recruited to the specific site by guide RNA and then cleaves DNA. Similarly to other nucleases, Cas9 can cleave off-target DNA targets in the genome at reduced frequencies. For application of Cas9, it is essential to consider ways to minimize the degree of off-target cleavage and to detect the presence of off-target cleavage.

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