Web Service Primary T cell REST Us

aka Primary T cell | Creative Biogene Add_annotation_inactiveAdd_annotation_inactiveLog in to add alternative_name
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Overview

Provider:
www-creative-biogene-com

Location:
United States Us

Submitter/Source:
Bennie GeorgeUs (2 months ago)

Base URL:
https://www.creative-biogene.com/crispr-cas9/service/gene-editing-in-primary-t-cells.html

Description(s):
by Bennie George (2 months ago)

The success of genome editing in primary T cell robustly promotes the development of CAR-T immunotherapy. In CAR-T cells, CAR gene can be delivered to a specific site within the genome by CRISPR/Cas9. Using CRISPR/Cas9 system reduces the risk of gene insertion at incorrect or undesired location. Meanwhile, CRISPR/Cas9 technology is used to knock out endogenous T cell receptor (TCR) and HLA class I (HLA-I) for reducing unwanted graft-versus-host reactivity.

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