Provider:
www-creative-biogene-com
Location:
United States
Submitter/Source:
creativebiogene (about 1 month ago)
Base URL:
https://www.creative-biogene.com/Human-ADRB2-Stable-Cell-Line-CHO-CSC-RG0058-195051-11.html
Documentation URL(s): None Login to add a documentation URL Description(s): creativebiogene(about 1 month ago)
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
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