Human KCNQ3/KCNQ5 Stable Cell Line-HEK293 REST

Provider:
www-creative-bioarray-com

Location:
United States

Submitter/Source:
Bennie George (16 days ago)

Base URL:
https://www.creative-bioarray.com/acroscell/human-kcnq3-kcnq5-stable-cell-line-hek293-acc-ri0147-item-63.htm

Documentation URL(s): Bennie George (16 days ago) https://www.creative-bioarray.com/acroscell/human-kcnq3-kcnq5-stable-cell-line-hek293-acc-ri0147-item-63.htm Login to add a documentation URL Description(s): Bennie George(16 days ago)

The human KCNQ3 and KCNQ5 genes encode the pore-forming subunits of Kv7.3 and Kv7.5, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive activity in neurons. Mutations in KCNQ3 that reduce M-current are responsible for some forms of benign familial neonatal seizure. Kv7.3/Kv7.5 channels expressed in neurons are therapeutic targets in seizure and cognitive impairment.

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