Provider:
www-creative-bioarray-com
Location:
United States
Submitter/Source:
Bennie George (16 days ago)
Base URL:
https://www.creative-bioarray.com/acroscell/human-kcnq2-kcnq3-stable-cell-line-hek293-acc-ri0145-item-65.htm
Documentation URL(s): Bennie George (16 days ago) https://www.creative-bioarray.com/acroscell/human-kcnq2-kcnq3-stable-cell-line-hek293-acc-ri0145-item-65.htm Login to add a documentation URL Description(s): Bennie George(16 days ago)
The human KCNQ2 and KCNQ3 genes encode the pore-forming subunits of Kv7.2 and Kv7.3, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive neuronal activity. Mutations in KCNQ2 or KCNQ3 that reduce M-current amplitude are responsible for some forms of benign familial neonatal seizure. Kv7.2/Kv7.3 channels are therapeutic targets in seizure, stroke, migraine, dementia, bipolar disorder, anxiety, and neuropathic pain.
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