WU-BLAST (SOAP) SOAP

WU-BLAST (Washington University Basic Local Alignment Search Tool) Version 2.0 is used to compare a sequence with those contained in nucleotide and protein databases by aligning the sequence with previously characterized genes. The emphasis of this tool is to find regions of sequence similarity, which will yield functional and evolutionary clues about the structure and function of this novel sequence. Regions of similarity detected via this type of alignment tool can be either local, where the region of similarity is based in 1 location, or global, where regions of similarity can be detected across otherwise unrelated genetic code.

WU-BLAST and NCBI BLAST are distinctly different software packages, although they have a common lineage for some portions of their code, so the services do their work differently, obtain different results and offer different features.

Free.

E-mail supplied for submission must be a valid e-mail address and no more than 25 concurrent jobs should be submitted at any one time, see http://www.ebi.ac.uk/Tools/webservices/about/webservices and the EMBL-EBI Terms of Use: http://www.ebi.ac.uk/Information/termsofuse.html

Goujon M., McWilliam H., Li W., Valentin F., Squizzato S., Paern J. and Lopez R. (2010) “A new bioinformatics analysis tools framework at EMBL-EBI.” Nucleic Acids Res. 38:W695-9 PMID: 20439314 (http://www.ebi.ac.uk/citexplore/citationDetails.do?externalId=20439314&dataSource=MED) DOI: 10.1093/nar/gkq313 (http://dx.doi.org/10.1093/nar/gkq313)

Lopez R., Silventoinen V., Robinson S., Kibria A. and Gish W. (2003) “WU-Blast2 server at the European Bioinformatics Institute.” Nucleic Acids Res. 31(13):3795-8 PMID: 12824421 (http://www.ebi.ac.uk/citexplore/citationDetails.do?externalId=12824421&dataSource=MED) DOI: 10.1093/nar/gkg573 (http://dx.doi.org/10.1093/nar/gkg573)