Web Service Human P2RY1/Clytin Stable Cell Line-1321N1 REST Us

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Bennie GeorgeUs (7 months ago)

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by Bennie George (7 months ago)

P2Y1 is a GPCR that binds to ADP and ATP, and couples to activate Gq. A wide variety of cells and tissues express P2Y1. Vascular endothelium and smooth muscle cells express P2Y1, and mediate vascular tone both in the resting state and in thrombosis, when platelet-derived ATP and ADP are present at high local concentrations. In addition, activation of P2Y1 expressed on platelets leads to ADP-induced shape changes and aggregation.

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