Web Service Human PTGDR2/beta-Arrestin Stable Cell Line-U2OS REST Us

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Overview

Provider:
acroscell-creative-bioarray-com

Location:
United States Us

Submitter/Source:
Bennie GeorgeUs (27 days ago)

Base URL:
https://acroscell.creative-bioarray.com/human-ptgdr2-beta-arrestin-stable-cell-line-u2os-acc-rg1459-item-894.htm

Documentation URL(s):
None
Description(s):
by Bennie George (27 days ago)

The chemoattractant-homologous receptor expressed on TH2 cells (CRTH2, also known as DP2 and GPR44) serves as a receptor for prostaglandin D2 (PGD2) and has been reported to mediate PGD2-dependent migration of eosinophils. DP2 mediates the pro-inflammatory effects of PGD2 generated in allergic inflammation. 11-Dehydrothromboxane B2 (11-dehydro-TXB2) was found to be a full agonist of the DP2 receptor and hence might cause the receptor activation in cellular contexts where PGD-synthase is not present. Antagonism of the 11-dehydro-TXB2/DP2 axis may be of therapeutic relevance.

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